Australia's Cauldron Ferm announces that the Queensland Government, through its Industry Partnership Program (IPP), will support the development of the Cauldron Bio-fab, a precision fermentation manufacturing facility in Mackay.

Mrs. Julieanne Gilbert (L), Member for Mackay and Assistant Minister for State Development, Infrastructure, Industrial Relations and Racing; Michele Stansfield, co-founder and CEO of Cauldron; Belinda Hassen, Candidate for Mackay, and Robin Stinson (R), CFO at Mackay Sugar - Image courtesy of Cauldron

Fermentation

Cauldron Ferm to Develop Asia-Pacific’s Largest Precision Fermentation Facility Following Queensland Government Support

Australia’s Cauldron Ferm announces that the Queensland Government, through its Industry Partnership Program (IPP), will support the development of the ‘Cauldron Bio-fab’, a precision fermentation facility in Mackay. The facility will be the first and largest end-to-end contract manufacturer for bioproducts in Asia-Pacific, with a projected annual output of over 1,000 tons. It will deploy Cauldron’s hyper-fermentation technology for cost-effective and resource-efficient production of alternative proteins and widely used petrochemicals for multiple sectors. Co-founder and CEO Michele Stansfield shares, “We are honored to be receiving support from the Queensland Government to develop our first industrial-scale operations in Mackay. This funding enables us to scale our innovative technology as a major milestone in our journey to redefine the scope of biomanufacturing.” Reaching price parity Cauldron aims to …

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Three bottles of animal-free milk

© Eden Brew

Fermentation

Government Support Crucial for Australia to Become a Global Precision Fermentation Leader, Says New CAA Report

The non-profit Cellular Agriculture Australia (CAA) has released a new white paper highlighting Australia’s capabilities in producing precision-fermented ingredients and its potential to become a global leader. The country is already home to a precision fermentation ecosystem of startups, established companies, research institutions, mature investors, and manufacturing capabilities. Eden Brew, Daisy Lab (NZ), All G Foods, Eclipse Ingredients, Nourish Ingredients, the ASX-listed company Noumi, and CMDO Cauldron Ferm contribute to making Australia and New Zealand’s precision fermentation sector the largest in Asia-Pacific. These companies focus on producing proteins such as whey and casein for dairy products and bovine lactoferrin, a sought-after whey protein due to its iron content, and fats to improve meat and dairy alternatives. Australia’s strong reputation as a global food supplier, established logistics networks, …

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The UK Government invests £12M in Cellular Agriculture Manufacturing Hub to cultivate meat at scale

© Mirai Foods

studies-numbers

Survey Explores Swiss Acceptance of Cultivated Meat and Precision Fermentation

On behalf of Swissveg, YouGov recently conducted a representative survey on the acceptance of cultivated meat and precision fermentation derived products in Switzerland. The survey found that flexitarians are most in favour of cultured meat. 47% of meat-reducers would buy such products if they were already available. The new products received the least approval from vegans and vegetarians with only 22%, but essentially, such products are not aimed at vegans and are essentially “real” meat without slaughter. While an average of 30% of respondents to the new Swissveg study would consume cultivated meat, the figure for 15 to 29-year-old Swiss is 46%. In contrast, only 19% of 60- to 79-year-olds would consume cultured meat. Cultivated meat in Switzerland Noteworthy in this context and pertaining to …

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The PHW Group will establish a new subsidiary focusing on traditional and precision fermentation to develop ingredients for alternative products.

© PHW Group

Fermentation

Poultry Giant PHW Enters Precision Fermentation Ingredients With New Subsidiary 

PHW Group, the largest poultry producer in Germany known for the Wiesenhof brand, will establish a new subsidiary later this year, focusing on traditional and precision fermentation to develop ingredients for alternative protein and blended products. The firm, which has invested millions in its plant-based meat brand Green Legend, intends to integrate plant-based, cultivated, and fermentation technologies under its roof to position itself as a critical player in the sector. As part of this expanding strategy, the company launched an ingredients platform in 2023 and recently invested in the Dutch company Mosa Meat, which focuses on cultivated beef and fats. “It is going to be a core technology” Marcus Keitzer, Board Member for Alternative Proteins at the PHW Group, told Cultivated X, “Precision fermentation technology …

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Governor JB Pritzker of llinois

Governor JB Pritzker ©illinois.gov

Cultivated, Cell-Cultured & Biotechnology

$51 Million Federal Grant for Precision Fermentation Hub to Drive Innovation, Growth, and Job Creation in Illinois

The Illinois Fermentation and Agriculture Biomanufacturing (iFAB) Tech Hub has secured approximately $51 million in federal funding from the US Economic Development Administration (EDA) as part of the Biden-Harris Administration’s Tech Hubs Program. The grant, which will support significant infrastructure expansions, aims to position Central Illinois as a global leader in biomanufacturing, promoting economic growth, job creation, and national security. The iFAB is supported by Innovate Illinois, a strategic initiative by Governor JB Pritzker and co-chaired by the University of Illinois Chancellor Robert J. Jones. Led by the Integrated Bioprocessing Research Laboratory (IBRL) at the University of Illinois Urbana-Champaign, it has secured over $680 million in cash match and strategic investments, demonstrating robust backing from multiple stakeholders. Governor JB Pritzker said, “Thanks to this $51 …

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South Africa’s Immobazyme, a precision fermentation company spin-off from Stellenbosch University, has raised $1.3 million in a recent investment.

© Immobazyme

Cultivated, Cell-Cultured & Biotechnology

South Africa’s Immobazyme Raises $1.3M to Boost Production of Precision Fermentation-Derived Proteins

South Africa’s Immobazyme, a precision fermentation company spin-off from Stellenbosch University, has raised $1.3 million in a recent investment round led by the University Technology Fund (UTF) with the participation of Innovus (University of Stellenbosch Enterprises). Immobazyme develops high-value proteins for various industries, including cultivated meat. The new capital will support the company’s production expansion, which includes doubling its current facility size and scaling its platform. This round brings its total raised capital to ZAR 24 million. “We’re incredibly grateful to all our investors and partners for recognizing the value and impact of our work. Daniel S., Wayne Stocks, and the rest of the team at The University Technology Fund (UTF), having you in our corner has been paramount to our success. A big thank you …

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Cultivated, Cell-Cultured & Biotechnology

Singapore Grants University of Illinois ARCS $14.8M to Launch Precision Fermentation Center

The team led by Professor Yong-Su Jin at the Illinois Advanced Research Center at Singapore (ARCS), an affiliated center of the University of Illinois Urbana-Champaign, has received a five-year, $14.8 million grant from Singapore’s National Research Foundation (NRF) to establish the Centre for Precision Fermentation and Sustainability (PreFerS). According to the announcement, the research at the new center will focus on microbial cell engineering or precision fermentation to convert readily available compounds like sugars into molecules, including alternative proteins, healthy fats, and vitamins. PreFerS aims to improve food supply chain resilience, reduce environmental impacts associated with food production, and address micronutrient deficiency, touted as the hidden hunger. Regarding its broader impact, the project aims to help Singapore achieve its goal of locally producing 30% of …

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Future Cow's co-founder Leonardo Vieira.

© Future Cow

Fermentation

Brazil’s First Precision Fermentation Startup Future Cow Prepares to Scale Up Production of Animal-Free Milk

Future Cow, a Brazilian food tech startup founded in 2023 by entrepreneur Leonardo Vieira and food scientist Rosana Goldbeck, aims to revolutionize dairy production with precision fermentation, creating real milk without cows. Considered Brazil’s first cellular agriculture startup using precision fermentation, Future Cow gained momentum through São Paulo’s Antler residency program, securing a $150,000 initial investment. Soon after, in a funding round led by Antler and Big Idea Ventures as part of the first cohort of the New Protein Fund II, it secured R$2 million (around $410,000) to accelerate its fermentation technology. Recently, the startup was selected for the FoodTech World Cup semi-finals, hosted by FoodHack and Givaudan. It has also been selected to participate in CNPEM’s Deeptech Acceleration Program (PACE), a local initiative that aims to boost …

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Michelin, Danone et al to open precision fermentation plant in France

© Michelin

Cultivated, Cell-Cultured & Biotechnology

Danone to Open Precision Fermentation Center ‘Biotech Open Platform’ in France with Strategic Players

French dairy giant Danone, engineered materials group Michelin, the US startup DMC Biotechnologies, and Crédit Agricole Centre France have partnered to create the Biotech Open Platform. The new center will focus on precision fermentation, a technology pivotal for innovation in agri-food and materials with the potential to address the need for sustainable alternatives to animal and fossil-based products, according to the announcement. Located in the commune of Clermont-Ferrand in Auvergne, at the Parc Cataroux Center for Sustainable Materials, an innovation accelerator supported by Michelin, the platform aims to support the development of biosolutions on a larger scale. Antoine de Saint-Affrique, CEO of Danone, said: “At Danone, we have always been focused on investing in the future of food, and this partnership is the next step in this …

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Plantbased Business Hour

Will 90% of Everything Be Made Through Precision Fermentation? Maria Cho, CEO of Triplebar, on The Plantbased Business Hour

Maria Cho, CEO of Triplebar is a guest on The Plantbased Business Hour. She and Elysabeth Alfano discuss the protein supply chain benefits provided by precision fermentation and when scaling will take place. Specifically, they discussed What is Triplebar, and precision fermentation? Why is this a critical pillar in the shift of global food systems transformation? What efficiencies does it allow? What kind of innovation will we see beyond the science? What applications in food will we see? When will this scale and see adoption? What impact will it have on lowering (or raising) the price of protein? We saw precision fermentation having a moment in 2019 with Perfect Day and The Every Company. Is this more advanced, differentiated in some manner? Is this considered clean …

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liberation labs precision fermentation plant

© Liberation Labs

Cultivated, Cell-Cultured & Biotechnology

Agronomics Invests $10M in Liberation Labs to Advance its 600,000 L Precision Fermentation Facility

Agronomics Limited (LSE: ANIC), the UK’s leading VC company focused on cellular agriculture and biomanufacturing, has invested $10 million in its portfolio company, Liberation Labs Holdings, a US biotechnology firm focused on large-scale precision fermentation manufacturing. The investment was part of a $12.5 million financing round, which was made through a Secured Convertible Promissory Note (SCPN) using Agronomics’ existing cash resources. Previous investor Siddhi Capital also joined the round to help fund the ongoing construction of Liberation Labs’s facility in Richmond, Indiana. Agronomics has invested $17.6 million in Liberation Labs, including $7 million to join the CDMO company on its mission to propel fermented proteins and other bio-based solutions. According to the announcement, Agronomics now holds a 37.5% stake in Liberation Labs. Jim Mellon, Executive …

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Nelida Leiva Eriksson, CEO of Ironic Foods

© Ironic Biotech

Fundraising

Ironic Biotech Raises €1M for Precision Fermentation-Derived Plant Proteins with High Iron Content

Swedish startup Ironic Biotech has received €1 million for its plant-based proteins, which are designed to facilitate the absorption of iron into the blood. Ironic’s proteins are produced by precision fermentation and used as ingredients for food or food supplements. The funds will be used for further development work, the expansion of the company’s patent portfolio, and the optimisation of the production process. The team is now looking for partners in the food and supplement industry with whom to collaborate. Addressing the performance gap Up to 25% of the world’s population suffers from iron deficiency, which can lead to severe fatigue, tiredness, heart palpitations, learning difficulties, and anaemia. “We want to help 2 billion people prevent and recover from iron deficiency and anaemia. Iron deficiency …

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A bowl with algae oil

© Checkerspot

Fermentation

Checkerspot and AAK to Produce Novel, Climate Change-Resistent Oils from Microalgae & Precision Fermentation

California’s Checkerspot and the Swedish company AAK have announced a partnership to develop, scale, and commercially produce novel algae oils for meat alternatives, plant-based food, and personal care products. Checkerspot makes renewable oils using microalgae and precision fermentation for materials and food, and AKK specializes in value-adding vegetable oils for food, confectionery, pharmaceuticals, and cosmetics. With this initiative, both companies aim to provide a sustainable alternative source of structuring fats and oils that can be manufactured at scale and are resistant to the impacts of climate change. Structuring fats and oils are used for products with healthier nutritional profiles, less fat, and better emulsion capabilities, including alt meat and bakery. Scott Franklin, co-founder & CSO of Checkerspot, shared: “Our team at Checkerspot is able to …

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BAIA Honey Panna Cotta

©BAIA/ MeliBio

Company News

MeliBio Partners with Pow.Bio to Advance Bee-Free Honey Through Precision Fermentation

MeliBio, a pioneering company in the production of bee-free honey, today announces a strategic collaboration with Pow.Bio to escalate precision fermentation capabilities. This partnership is set to further innovate the production of high-value bee proteins and enzymes, targeting the expansive global market for functional food ingredients. The collaboration leverages Pow.Bio’s expertise in both traditional and innovative continuous fermentation technology, incorporating artificial intelligence (AI) to optimize the fermentation process. This technological advancement is expected to commence this month, marking a critical phase in MeliBio’s scale-up efforts. MeliBio is at the forefront of creating honey products that do not rely on bees, thereby addressing the environmental impact on bee populations and promoting biodiversity. The company’s R&D team has completed initial proof of concept work, demonstrating the viability …

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Cauldron raises $9.5M AUD Series A to scale its continuous hyper-fermentation technology

Michele Stansfield, co-founder and CEO of Cauldron © Cauldron Ferm

Cultivated, Cell-Cultured & Biotechnology

Investors Back Cauldron’s Plans for Global Network of Precision Fermentation Facilities to Tune of $6.25M

Precision fermentation company Cauldron Ferm announces it has secured AUD 9.5 million ($6.25M) in a series A round led by Horizons Ventures. SOSV, In-Q-Tel, and previous investor Main Sequence also participated in the round, bringing Cauldron’s total raised funds to $20 million.  Precision fermentation is crucial for increasing food production without expanding agricultural land while it addresses sustainability and security issues. The United Nations predicts a 70% increase in food production by 2025 to support the rising population. Cauldron says that it aims to deploy its cost-effective, continuous fermentation technology in a network of worldwide rural facilities to develop biobased products and contribute to meeting the growing global food, cosmetics, and materials demand.  Chis Liu of Horizons Ventures, comments: “Precision fermentation is an amazing technology, because it enables bio based production of …

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(Left to Right): Dirk Steinhäuser, Vice Head, Dresden Engineering Office of Glatt Group; Alaa Al Ali, Shareholder and Member of the Board of Novel Foods Group LLC; Matthew Robin, Member of the Board of Bioengineering AG.

(Left to Right): Dirk Steinhäuser, Vice Head, Dresden Engineering Office of Glatt Group; Alaa Al Ali, Shareholder and Member of the Board of Novel Foods Group LLC; Matthew Robin, Member of the Board of Bioengineering AG © Novel Foods Group

Fermentation

Novel Foods Group Reveals $500M Precision Fermentation Hub to Produce Brazzein

Novel Foods Group, an Abu Dhabi-based company producing sweet proteins, has announced a landmark agreement to build the first phase of a $500 million biotech production hub in the United Arab Emirates (UAE) focused on precision fermentation. The deal was signed between Novel Foods Group, which is a subsidiary of the investment conglomerate Gewan Holding, Glatt Group, a German expert in plant engineering, BioEngineering AG, a Swiss company specialized in engineering and design, and CB Consultancy AG, a Swiss company engineering solutions for cutting-edge industries. The new production site will initially develop brazzein, a sweet-tasting protein found in the fruit of the native West African Oubli plant, that is said to be significantly sweeter than sugar. Local people have used and eaten the fruit for many …

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Governor JB Pritzker iFab tech hub illinois

Governor JB Pritzker © @GovPritzker on Twitter

Cultivated, Cell-Cultured & Biotechnology

Illinois Invests $680M in Biotechnology Sector to Enhance Biomanufacturing and Precision Fermentation Capabilities

The state of Illinois is set to advance in the biotechnology sector through a substantial government investment strategy, enhancing its biomanufacturing and precision fermentation capabilities. The initiative, led by Governor JB Pritzker in partnership with Innovate Illinois, involves an allocation of $680 million to create the Illinois Fermentation and Agriculture Biomanufacturing (iFAB) Tech Hub, supported by both public and private funding. Governor Pritzker claims that the vision for iFAB is to support the state’s broader goals of becoming a central figure in the global biomanufacturing landscape over the coming decade. He states, “Home to world-class institutions, modernized infrastructure, and first-rate research centers, Illinois is transforming technology, biomanufacturing, and innovation at every turn.” The governor further underlined the transformative potential of iFAB, positioning it as a …

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Cellular Agriculture Australia (CAA) announces the release of a pioneering Regulation Resource Hub to help cell ag companies streamline their food safety application process for novel foods.

© Cellular Agriculture Australia (CAA)

Fermentation

This Week in Australia’s Cell Ag Sector: Cauldron Ferm and QUT Lead Efforts to Scale Precision Fermentation Production

We are covering this week’s developments in Australia’s cellular agriculture ecosystem, with Cauldron Ferm and Queensland University of Technology (QUT) leading efforts to establish a global infrastructure for scaling up precision fermentation production for the Asia-Pacific region. Cauldron Ferm Receives License to Produce Animal-Free Proteins at 10,000 L Scale Precision fermentation company Cauldron Ferm announces that it has received a license from the Office of the Gene Technology Regulator (OGTR) to produce animal-free proteins at a 10,000 L scale. The DIR200 license allows Cauldron to utilize its proprietary hyper-fermentation technology and Pichia Pastoris yeast to produce dairy, egg, and spider-silk proteins. The OGTR, part of the Australian Government’s Department of Health and Aged Care, conducted the pertinent risk and management assessments, determining that Cauldron’s hyper-fermentation process is …

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New Culture block of grating cheese on chopping board

© New Culture

Fermentation

What is Precision Fermentation? Precision Fermentation Alliance and Food Fermentation Europe Reveal Expanded Definition 

Trade organizations the Precision Fermentation Alliance (PFA) and Food Fermentation Europe (FFE) have revealed a new expanded definition of precision fermentation (PF) to provide clarity on its unique characteristics, its differences from other fermentation-based technologies, and its applications. With biomass fermentation, traditional fermentation, and other technologies like molecular farming and plant cell culture emerging to make novel ingredients for food, the collaboration aims to help stakeholders, regulators, and consumers understand the basics of PF technology. Recently, precision fermentation has been in the spotlight, with various companies announcing the launch of animal-free dairy proteins, human milk fat analogs, and proteins for eggs. However, before its emergence for alt proteins, the technology has been safely used in food and medicine for over three decades to make insulin, rennet …

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Fengru Lin, TurtleTree CEO and co-founder

Fengru Lin, TurtleTree CEO and co-founder © TurtleTree

Fermentation

TurtleTree Secures First-Ever Vegan Certification in Precision Fermentation Dairy

After obtaining self-GRAS status last November for its animal-free lactoferrin, LF+, TurtleTree, a Singaporean biotech company operating in California, USA, announces that the product has officially obtained vegan certification.  TrutleTree’s protein and manufacturing process has been certified by Vegan Action, the leading vegan certification provider in the US. The vegan stamp ensures that consumers can trust the absence of animal products, byproducts, and animal testing in their products. According to the Singaporean biotech, this milestone establishes it as the first precision fermentation dairy company globally to obtain vegan certification. Meanwhile, it also marks the first time that Vegan Action gives the stamp to a novel protein in its 24-year trajectory with more than 15,000 products Vegan Certified. Fengru Lin, CEO and co-founder of TurtleTree, comments: …

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