Vivici fermentation unit

© Vivici

Global Biomanufacturing Capacity Must Grow 20X to Reach Industry Growth of $200 Billion by 2040, Says New Report

A recent report, co-authored by the New York-based biotech firm Synonym and Boston Consulting Group, has outlined a roadmap for the biomanufacturing industry, predicting a potential explosion to a $200 billion market in specialty sectors over the next ten years. The report Breaking the Cost Barrier on Biomanufacturing encourages the transition to biomanufacturing to address issues of sustainability and cost-efficiency in current industrial production methods. However, the report’s estimated $200 billion market value is focused on precision fermentation to produce food ingredients, chemicals, and chemical precursors. According to the authors, the figure is considered conservative and reflects only a fraction of the potential for growth within the industry. “The big problem—and the reason that precision fermentation remains an underused technology despite continuing advances in genome engineering and …

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New Culture block of grating cheese on chopping board

© New Culture

What is Precision Fermentation? Precision Fermentation Alliance and Food Fermentation Europe Reveal Expanded Definition 

Trade organizations the Precision Fermentation Alliance (PFA) and Food Fermentation Europe (FFE) have revealed a new expanded definition of precision fermentation (PF) to provide clarity on its unique characteristics, its differences from other fermentation-based technologies, and its applications. With biomass fermentation, traditional fermentation, and other technologies like molecular farming and plant cell culture emerging to make novel ingredients for food, the collaboration aims to help stakeholders, regulators, and consumers understand the basics of PF technology. Recently, precision fermentation has been in the spotlight, with various companies announcing the launch of animal-free dairy proteins, human milk fat analogs, and proteins for eggs. However, before its emergence for alt proteins, the technology has been safely used in food and medicine for over three decades to make insulin, rennet …

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Prefer bean-free coffee

© Prefer

Prefer Raises $2M for Bean-Free Coffee Made With Upcycled Ingredients & Fermentation

Singapore-based startup Prefer has raised $2 million to scale up the production of its bean-free coffee. The round was led by Forge Ventures, with participation from Better Bite Ventures, Sopoong Ventures, SEEDS Capital, Entrepreneur First, and Pickup Coffee. Prefer’s coffee alternative is made by using microbes to ferment upcycled ingredients such as waste bread, soy milk pulp, and spent brewer’s grain. The resulting mixture is then roasted and ground, using a proprietary process that provides a similar taste and aroma to conventional coffee. Sustainable and affordable The aim is offer a more sustainable alternative to coffee, which has a high carbon footprint and is heavily affected by climate change. Changing weather patterns and increased demand are expected to drive up coffee prices in the coming …

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the Chinese startup will launch the 70/30 Mycelium Research Lab, located within a renowned biotech startup incubator,

© 70/30 Food Tech

70/30 Food Tech to Launch Mycelium Research Lab to Create Affordable Proteins for Asia

Shanghai-based 70/30 Food Tech, a 100% plant-based ready meal company and a producer of plant, fungi, and mycelium-based ingredients, announces that it has completed a seed-extension fundraising round (the raised amount has not been disclosed). With the funds, the Chinese startup will launch the 70/30 Mycelium Research Lab, seemingly located in Bangalore, India, within a renowned biotech startup incubator to develop cost-effective fungi-based biomass ingredients for alternative meats. With this expansion, the startup will have a presence in two important Asian markets. According to the press release, the funding round received strong backing from investors, with participation from Better Bite Ventures and support from previous seed investors. “We believe that mycelium-based sustainable protein products can be a gateway to broader consumer adoption in Asia, especially given …

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Vivici whey protein

© Vivici

Vivici Launches Nature-Identical Whey Protein Made Using Fermentation

Vivici, a Netherlands-based producer of animal-free dairy proteins, has commercially launched its nature-identical whey protein made using precision fermentation. The protein is an isolate of beta-lactoglobulin, the major whey protein in cow’s milk. It contains all amino acids required by the human body and has high levels of leucine and branched-chain amino acids. The protein is also free of lactose, cholesterol, hormones, and antibiotics, and is said to be rapidly absorbed in blood plasma. In the US, the product has self-affirmed GRAS (Generally Recognized as Safe) status. It provides a more sustainable alternative to conventional whey protein, with a neutral color and taste ideal for use in protein beverages, powders, and bars. “Nutritionally, Vivici’s beta-lactoglobulin isolate is superior to plant protein isolates, even outperforming whey …

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Pacifico Biolabs, a Belin-based biotech startup, announced that it raised $3.3 million to make mycelium-based whole-cut alternatives.

© Viktor Strasse

Pacifico Biolabs Secures $3.3M to “Transform Seafood” with Whole Cut Alternatives

Berlin-based biotech startup Pacifico Biolabs emerges from two years in stealth mode with the announcement of a $3.3 million oversubscribed pre-seed round.  With the capital, the startup plans to improve and further scale its “unique” biomass fermentation process to make mycelium-based whole-cut alternatives, starting with seafood. In addition, it will expand its team with key positions, such as a CTO and chief of staff. Simon Capital and FoodLabs led the funding round, joined by Exceptional Ventures and Sprout & About Ventures. Patrick Noller, General Partner at FoodLabs, comments, “We are confident that Pacifico’s technology strongly positions them to transform seafood and beyond, addressing the urgent demands of a changing climate.”  Friedrich Droste, Managing Partner of Simon Capital, shared, “Their innovative technical approach to alternative seafood …

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Superbrewed foods logo rectangle

© Superbrewed Foods

Superbrewed Food Partners with Döhler to Offer Sustainable Proteins to the Food and Beverage Industry

Superbrewed Food, a biomass fermentation startup based in Delaware, announces a partnership with Döhler GmbH, a global manufacturer, marketer and supplier of natural ingredients for the food, beverage and nutrition industries. As a manufacturing partner, Döhler will provide extensive fermentation capabilities for the production of Superbrewed Food’s patented postbiotic protein ingredient, which will be launched in 2024 in various food categories in the US by multiple food manufacturers. Postbiotic protein free of animal substances Superbrewed Food offers a natural, postbiotic protein that is free from animal derivatives and allergenic substances, and is non-GMO. This postbiotic protein, comprising over 85% protein, is enriched with essential and branched-chain amino acids. It as a complete food rather than an isolated protein, containing significant levels of essential minerals and …

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A chicken alternative made with ABUNDA

© ENOUGH

UK Mycoprotein Startup ENOUGH Signs Commercial Deal with Cargill

Food tech company ENOUGH announces that it has extended its partnership with agribusiness giant Cargill. Through the deal, Cargill is to sign a commercial agreement to use and market ENOUGH’S mycoprotein ingredient ABUNDA and to invest in its recent Series C round. ABUNDA is described as a highly versatile ingredient that provides all nine essential amino acids and dietary fiber. It is said to have a neutral taste, making it highly versatile in multiple applications. ENOUGH leverages biomass fermentation to produce its signature product at a large scale. The protein is grown by feeding fungi renewable feedstocks to make a sustainable food protein source.  Upscaling in Europe ENOUGH states that its collaboration with Cargill, “benefiting from its global footprint and feedstock technology expertise,” will allow it to …

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Fengru Lin, TurtleTree CEO and co-founder

Fengru Lin, TurtleTree CEO and co-founder © TurtleTree

TurtleTree Secures First-Ever Vegan Certification in Precision Fermentation Dairy

After obtaining self-GRAS status last November for its animal-free lactoferrin, LF+, TurtleTree, a Singaporean biotech company operating in California, USA, announces that the product has officially obtained vegan certification.  TrutleTree’s protein and manufacturing process has been certified by Vegan Action, the leading vegan certification provider in the US. The vegan stamp ensures that consumers can trust the absence of animal products, byproducts, and animal testing in their products. According to the Singaporean biotech, this milestone establishes it as the first precision fermentation dairy company globally to obtain vegan certification. Meanwhile, it also marks the first time that Vegan Action gives the stamp to a novel protein in its 24-year trajectory with more than 15,000 products Vegan Certified. Fengru Lin, CEO and co-founder of TurtleTree, comments: …

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Slice of pizza with melting New Culture cheese

© New Culture

New Culture Announces “World First” GRAS Status for Precision Fermentation Casein, Paving the Way for Animal-Free Mozzarella

Following a review by an independent panel of qualified scientific and toxicology experts, Californian animal-free cheese producer New Culture announces that it has self-affirmed its precision fermentation-derived casein as Generally Recognized as Safe (GRAS).  New Culture claims this achievement marks the “world’s first” GRAS designation for animal-free casein, which allows it to sell its products containing casein in the USA. New Culture has yet to notify the FDA through the GRAS Notification Program. It is worth noting that this step is not mandatory; however, the FDA strongly encourages manufacturers to contact the agency by submitting a notice. Inja Radman, co-founder and CSO of New Culture, shares: “Having secured another ‘world’s first’ for our animal-free casein is a testament to the hard-working and innovative team we have …

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mushroom

©MycoTechnology

Food Ingredients from Precision Fermentation to Reach $31.2Bn with Mushrooms as Largest Segment

Market research firm Research and Markets has published a new trend report on the global precision fermentation ingredients market. According to the report, the global market could reach an estimated value of $31.2 billion by 2030, with a strong compound annual growth rate (CAGR) of 42.6% between 2024 and 2030. The future of the global precision fermentation ingredients market looks promising, says the report, with opportunities in the food and beverage, pharmaceutical and cosmetics markets. The key drivers for this market are increasing consumer demand for sustainable and ethically sourced ingredients, growing awareness of health benefits, and ongoing advances in biotechnology and fermentation processes. According to the authors of the new report, mushrooms will remain the largest segment in the market during the forecast period. …

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Girl drinking milk in school

© Lightfield Studios - stock.adobe.com

Canada’s Renaissance BioScience Receives Government Funding to Develop Yeast Solution for the Off-Flavors of Plant Proteins

The Vancouver-based yeast bioengineering company Renaissance BioScience has been awarded CAD $232,000 in funding from the Canadian Food Innovation Network to develop a revolutionary product for plant-based protein products.  Renaissance is working on a pioneering project with food industry partners to develop and commercialize a non-GMO solution to neutralize compounds that lead to off-flavors and undesirable aromas in plant-based flours and proteins. In addition to enhancing taste, the yeast aims to eliminate the need for commonly used “flavor masking” ingredients by providing a clean-label solution for manufacturers; on a product’s ingredient list, the yeast solution will be simply identified as “yeast.” Better flavor for a growing market Despite the health and sustainability benefits that plant-based alternatives to animal products offer, widespread consumer acceptance is hindered …

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Yali Bio team

Yali Bio team © Yali Bio

Yali Bio Unveils Game-Changing Human Breast Milk Fat from Yeast, Set to Transform Nutritonal Value of Infant Formula

Yali Bio, a US biotech startup developing climate-smart ingredients using yeast in precision fermentation, announces a new game-changing development for infant nutrition: a bioidentical analog of human breast milk fat known as OPO. Yali Bio says that its yeast-derived OPO will optimize and enhance the nutritional value of infant formulas, improving infant health outcomes; according to the World Health Organization (WHO), 130 million newborn babies are fed infant formula at least partially. OPO, scientifically termed 1,3-dioleolyl-2-palmitate, is naturally found in high concentrations in breast milk and plays a crucial role in nutrient absorption and the overall health of infants. However, according to Yali Bio, a cost-effective source of OPO for infant formula has yet to be available, with most products relying on fats derived from …

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Remilk has become the first company to receive the green light in Canada for a precision fermentation-derived protein.

Image courtesy of Remilk

Remilk Receives No Objections Letter for Sale of Animal-Free Milk Protein, Heralding “New-Dairy Revolution” in Canada

Israeli biotech company Remilk announces that it has obtained Health Canada’s “Letter of No Objection,” allowing the use and commercialization of its animal-free milk protein called BLG within Canada. With this achievement, Remilk has become the first company to receive the green light in the country for a precision fermentation-derived protein.  According to the announcement, Health Canada conducted a thorough evaluation and deemed Remilk’s animal-free protein safe for consumption. As a result, Canada has opened the door for new dairy products, including milk, ice cream, yogurt, and cream cheese, made with novel proteins instead of traditional milk proteins. “This is an important day for us at Remilk, and a historic one for Canada as it opens its doors to the new-dairy revolution. We developed a strategic roadmap for …

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Superbrewed Food

© Superbrewed Food

Revolutionizing Alt-Proteins: Superbrewed Food Secures Patent for “True Breakthrough” Postbiotic Protein

Fermentation startup Superbrewed Food has achieved a major milestone, securing a patent for its proprietary Postbiotic Protein ingredient. This development, combined with the attainment of self-affirmed GRAS status, grants the company a competitive advantage in the alt-protein market, enhancing the appeal of Superbrewed Postbiotic Protein to consumer packaged goods (CPG) companies. The patent comes after a period of significant growth for Superbrewed Food. In 2022, the company attained self-affirmed GRAS status for its postbiotic protein and began a strategic collaboration with The Bel Group, makers of Babybel and The Laughing Cow, to develop cheese products with its postbiotic cultured protein. Superbrewed Food also made an appearance at the UN Climate Conference (COP28) in 2023. The US Patent Application Publication (No. 2023/0320399) covers a broad range …

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Belgium’s Deputy Prime Minister Petra De Sutter at the inauguration – Image courtesy of Paleo

Paleo Opens New Facility in Belgium for Animal-Free Heme, Reveals Expansion Plans for 2024

On the back of its successful €12 million funding round last year, biotech company Paleo has opened a new pilot-scale facility in Leven, Belgium, at the Bio-Incubator Leuven.  The company, which specializes in developing proteins via precision fermentation, aims to use the new laboratory facilities to accelerate the production and commercialization of its flagship product, animal-free heme. Speaking to vegconomist, the company outlined its plans for 2024, including making significant progress in bringing its products to market and preparing for a Series B investment round. Last year, the company opened an office in Singapore to serve future activities in the Asia-Pacific region, where market approval for novel foods takes less time than in Europe. Expansion of the leadership team As part of the 2024 strategy, Paleo …

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21st.BIO's team

© 21st.BIO

21st.BIO Opens Access to its Large-Scale Production Platform for Animal-Free Dairy Proteins

21st.BIO, a Danish bioproduction firm offering integrated end-to-end services, announces that it is granting access to its precision fermentation technology platform to produce animal-free dairy proteins. The new service aims to offer ingredient manufacturers, from startups to leading companies, cost-effective solutions to accelerate the development of sustainable dairy proteins at a competitive cost. 21st.BIO states it has the industry’s most advanced precision fermentation technology platform for large-scale production. Its fermentation technology is partly licensed from Novonesis (a merger of Novozymes and Chr. Hansen Holding), which has developed its platform over several decades to produce food-grade ingredients. Thomas Schmidt, CEO of 21st.BIO, comments: “We founded 21st.BIO with one simple mission: to make precision fermentation technology accessible to as many companies as possible, so they can successfully take their …

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Phytolon

© Phytolon

Ginkgo Bioworks and Phytolon Partnership Unlocks Full Yellow-to-Purple Spectrum in Natural Food Colors

Ginkgo Bioworks and Phytolon have announced the successful completion of the first development milestone in their partnership, unlocking the full color palette of the yellow-to-purple spectrum accessible for Phytolon’s natural food colors. Phytolon’s natural betalain pigments, derived from foods like beets and cactus fruit, present a safe and sustainable alternative to synthetic dyes. With heightened scrutiny and bans on synthetic dyes, this new innovation aims to address growing regulatory concerns and consumer demand for nature-derived products. After being founded in 2018, Phytolon secured $4.1 million in 2020 to bring its fermented food colors to market, focusing on product development and refining its fermentation technology. The company has been actively seeking partnerships ever since to enhance its technology and expand its market reach. The partnership with …

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The Checkerspot team

The Checkerspot team © Checkerspot

Checkerspot Unveils “Breakthrough” for Baby Formula: Human Milk Fat Analog Made Using Microalgae Fermentation

California’s Checkerspot, a biotechnology firm that produces renewable oils by fermentation of microalgae, announces the development and large-scale production of fat analog that the company claims mimics the human milk fat known as OPO (Oleic-Palmitic-Oleic or sn-2 palmitate).  According to the company, this “breakthrough” achievement will revolutionize infant nutrition with essential lipids that contribute to better digestion and nutrient absorption and potentially offer long-term health benefits for infants. Making a human milk triglyceride Checkerspot has developed a technology that can accurately modify specific fatty acids in a living organism to create triglyceride structures with precise distribution at the molecular level. This capability allows for the production of OPO’s analog. The biotech has also been able to scale its fermentation platform, allowing for the production of fats at …

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A fat developed using precision ferementation by the German startup Zayt Bioscience.

© Zayt Bioscience

Zayt Bioscience Creates Fermented Fats to Combat Deforestation in Food Industry

Amr Aswad and Venkat Konasan founded the biotech startup Zayt Bioscience in Berlin, Germany, to create a new generation of fermented fats that do not come from agricultural commodities. Palm and soybean oilseeds are the primary sources of oil, an essential product for food production, from chocolates to biscuits to margarine and frying fats. Additionally, plant oils find applications in various industries, such as cosmetics, cleaning products, and biofuel production. However, according to an Our World in Data report, palm and soybean crops account for 18% of global deforestation annually, mainly in the global south. Backed by the VC FoodLabs in a pre-seed funding round, Zayt Bioscience developed a patent-pending precision fermentation platform that uses microbes and fruit waste to make alternatives to palm oil and margarine. The proof of concept of the …

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