The Cultivated B

The Cultivated B siemens hannover messe

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Fairs & Events

n!Biomachines and Siemens Focus on Simplifying Biomanufacturing for Alternative Proteins

At the ongoing Hannover Messe, The Cultivated B and Siemens have teamed up to present advancements in biomanufacturing for the alternative protein sector. The companies are showcasing their AUXO V® bioreactor, a key technology aimed at scaling alternative protein production through economically sustainable methods. n!Biomachines, a subsidiary of The Cultivated B, is at the forefront of developing bioreactors designed for the food industry and other sectors. These bioreactors play a central role in producing proteins traditionally sourced from animals, but through biomanufacturing methods that eliminate the need for animal agriculture. The bioreactors are built with an emphasis on scalability, precision, and ease of use, allowing for the transition from lab-scale production to industrial-level output. Hamid Noori, CEO of n!Biomachines, commented on the partnership with Siemens, …

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The Cultivated B

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Manufacturing & Technology

The Cultivated B Unveils Synthetic Growth Factor to Reduce Cultivated Meat Costs

Biomanufacturing company The Cultivated B has developed a synthetic molecule that could significantly reduce the cost of growing cells for cultivated meat, biopharmaceuticals, and other cell-based industries. The newly identified molecule, TCB-32, functions as a replacement for basic fibroblast growth factor (bFGF), a key ingredient in cell culture that stimulates cell growth but is expensive and unstable. Addressing challenges in cell culture Producing cultivated meat requires growing large numbers of cells in bioreactors. One of the biggest challenges is the high cost of growth factors like bFGF, which are essential for cell proliferation but difficult to produce consistently. bFGF is also fragile—it breaks down quickly, requiring frequent replenishment, which further increases costs. The Cultivated B’s research team has identified TCB-32, a synthetic small molecule that …

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The Cultivated B auxo bioreactor

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Manufacturing & Technology

The Cultivated B Unveils AI-Driven Biosensors to Advance Fermentation Tech

Biotechnology company The Cultivated B has introduced a new AI-driven biosensor system designed to enhance real-time monitoring of cell culture and fermentation processes. The multi-channel biosensors aim to improve bioprocess transparency, allowing engineers to track growth and metabolic activity with high precision. The system integrates real-time data analytics with continuous, high-resolution monitoring, eliminating the need for manual sampling or physical probes. This approach reduces contamination risks while ensuring consistent process conditions. The biosensors are designed to detect specific molecules within a bioreactor, offering a customizable solution that adapts to various bioprocessing requirements. The technology can measure a range of chemicals, including glucose, amino acids, and lactic acid, at concentrations below the picomolar level. “The release of highly advanced biosensors is another crucial step towards our …

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DTU Biosustain facility

DTU Biosustain © The Cultivated B
Cultivated, Cell-Cultured & Biotechnology

Industry & Academia Research: The Cultivated B and DTU Biosustain to Take Bioreactors to the “Next Level”

In a collaboration between industry and academia to accelerate progress in cell-based foods, the German cell ag technologies specialist The Cultivated B (TCB) and The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) will work to drive innovation and advance the field of bioreactor design. The agreement, signed into a Memorandum of Understanding, will test and improve TCB’s AUXO V bioreactor technology and set new industry standards for bioprocessing.  The Cultivated B develops cell ag technology, bioreactor engineering, and cultivated meat products. Its development team is located in Germany, with two subsidiaries in Canada, PreFer Industries and n!Biomachines. Bo Skjold Larsen, CEO at DTU Biosustain, emphasized that collaboration between academic researchers and industry professionals helps speed progress, encourages innovation, and positively affects society.   “We are looking forward to collaborating with …

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Dr. Wolfgang Kühnl, CEO & owner, InFamily Foods Holding & co-founder of The Cultivated B

Dr. Wolfgang Kühnl, Co-founder ©The Cultivated B
Cultivated, Cell-Cultured & Biotechnology

The Cultivated B: “There Will Be No Sustainable Protein Future Without a Sustainable Business Model”

Dr Wolfgang Kühnl is the managing partner of Germany’s InFamily Foods Holding GmbH & Co. KG. The son of an entrepreneurial family, Dr Kühnl studied food technology and biotechnology at the Technical University of Munich and completed his doctorate at the Chair of Food Process Engineering and Dairy Technology. In 2011, Dr Wolfgang Kühnl joined his parents’ company H. Kemper GmbH & Co. KG, which he has managed as a managing partner since 2015. Since 2020, Dr Wolfgang Kühnl has been one of two Managing Partners of InFamily Foods Holding, which was formed from the merger with Reinert. The group of companies consists of The Family Butchers (animal protein products), The Plantly Butchers (plant-based protein products), and The Cultivated B (alternative protein sources). With The …

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The Cultivated B. facility in Germany

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Company News

The Cultivated B. Achieves ISO Certification for Quality Management and Efficiency

German bioengineering company The Cultivated B. (TCB) announces the achievement of a significant milestone: obtaining the ISO 9001:2015 certification.  This globally recognized standard for quality management aims to demonstrate a company’s commitment to efficiently and effectively meeting the needs of its customers and stakeholders.  Valid for three years, this ISO certification underscores TCB’s commitment to quality management, operational efficiency, innovation, and customer satisfaction. According to the company, the certification process involved a comprehensive audit of the company’s operations, including developing a robust quality management system and detailed process documentation across all departments. As explained by ISO, implementing ISO 9001 signifies that an organization has established efficient processes and adequately trained employees to deliver high-quality products or services consistently. Dr. Hamid Noori, CEO of The Cultivated B., shares, …

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The Cultivated B Canada, a subsidiary of Germany’s The Cultivated B, has been renamed as n!Biomachines.

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Company News

The Cultivated B Canada Rebrands to n!Biomachines, Pioneering Fit-for-Purpose Bioreactors

The German biotech The Cultivated B. announces that its subsidiary The Cultivated B Canada has been rebranded to n!Biomachines to reflect its mission in bioreactor engineering for successful biomanufacturing. (The notation ‘n!’ represents ‘factorial’, hence the name can be read as ‘factorial biomachines.’) n!Biomachines, located in Burlington, Ontario, develops and manufactures fit-for-purpose, affordable, and automated bioreactors, to enable the commercial scalability of cellular agriculture-derived ingredients for for food, dietary supplements, cosmetics, and more. The Cultivated B. opened its bioreactor facility in 2022, as part of a strategic partnership with Ontario Genomics, a government-funded non-profit, to develop the economic potential of the cell ag industry.  Hamid Noori, CEO of n!Biomachines and The Cultivated B., comments: “The mathematical term, ‘n!’, or n factorial, acknowledges the core of our mission: scalability and …

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Czech startup Bene Meat Technologies (BMT) has become the first company in the world to obtain EU Certification to produce and sell cultivated meat for pet food.

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Cultivated, Cell-Cultured & Biotechnology

Has Cultivated Meat for Pet Food Really Been Approved in EU? The Complicated Story of Bene Meat (and Others in the Space)

Two weeks ago, a press release was widely distributed by Czech startup Bene Meat Technologies, titled “Bene Meat Technologies is the first company in the world to be licensed to produce and sell cultured meat as dog and cat food” The release stated, ” On 7.11.2023, the Czech startup Bene Meat Technologies (BMT) won the world championship to produce and sell cultured meat for PET FOOD needs. With the certification obtained from the European Feed Materials Register, it becomes the only entity in the world that can produce and sell this product for PET FOOD needs.[…] Bene Meat Technologies is thus the first entity in the world to be authorised to produce and sell cultured meat for PET FOOD.”  This apparently groundbreaking news was covered …

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The Cultivated B. facility

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Company News

The Cultivated B. Enters Pre-Submission Phase for Approval of Cultivated Meat in Europe

The Cultivated B — the cultivated meat subsidiary of Germany’s second-largest animal-based sausage manufacturer Infamily Foods — states it has entered the pre-submission phase of regulatory approval for the sale of hybrid cultivated meat products in Europe. The company explains that it has entered the initial stage, which is an official EFSA process requested at least six months in advance of the official submission. After the application is submitted, TCB would become the world’s first biotech company to apply for EFSA certification for cultivated meat, if there have been no further applications in this period. It should be noted here that while Aleph Farms did apply for regulatory approval in Switzerland this July, marking it the first-ever submission for cultivated meat in Europe, this application …

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Founder, The Cultivated B.

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Cultivated Meat

The Cultivated B Partners with denovoMATRIX to Explore Large-Scale Cultivated Meat Production

German bioengineering company The Cultivated B (TCB) announces a partnership with biotech and biomaterials company denovoMATRIX to explore the possibilities of cultivating meat on a large scale, economically, for commercial purposes.  The companies will conduct a joint feasibility study using microcarriers to overcome the limitations of growing cells in suspension. Their goal is to establish a pilot-scale cell manufacturing that can be adopted as a standard to cultivate meat at scale successfully. Dr. Hamid Noori, CEO of The Cultivated B, comments, “This collaboration not only signifies a step forward in cell line technology but also reflects our mutual dedication to progressive innovation in the cultivated meat sector.” B2B technology providers The collaboration leverages the technical competencies of the two German B2B technology providers. denovoMATRIX will …

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