Cell lines

The APAC Regulatory Coordination Forum has released two white papers addressing essential safety and regulatory concerns for cultivated meat.

© APAC Regulatory Coordination Forum
Cultivated Meat

APAC Regulatory Coordination Forum Releases White Papers to Harmonize Cultivated Meat Standards

The APAC Regulatory Coordination Forum has released two white papers that address essential safety and regulatory concerns for cultivated meat to support their commercialization while promoting safe innovations in the Asia-Pacific market. The new resources examine current gaps in cell line developments and cell culture media components — the building blocks of cultivated meat production — identified as the two regulatory topics of highest interest in 2024. The cell line development paper focuses on issues related to cell line documentation, stability, genetic modification, and trade requirements for cultivated food production. Meanwhile, the cell culture media paper addresses safety assessment protocols, evaluation of expression systems for media substances, categorization of media components, quality standards, genetic engineering standards, and conformity assessment procedures. The papers were developed with …

more

Organisations and brands:

Dominic Jeong, CEO of Simple Planet.

CEO Dominic Jeong © Image courtesy of Simple Planet

Company News

Simple Planet to Develop Cell Ag Technologies Under South Korea’s National Project for Food Tech

Cultivated meat ingredients developer Simple Planet announces that it has been selected to participate in an ₩11 billion national project launched by South Korea’s government to expand the food tech industry. The national project involves various individual projects led by different governmental institutions, including the Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry (IPET), the Korea Agriculture Technology Promotion Agency (KOAT), and the Korea Institute of Marine Science and Technology Promotion (KIMST).   As Simple Planet explained to Cultivated X, the company will be developing cell ag technologies for different purposes: The first project under the umbrella of KOAT’s agri-food venture nurturing program will focus on cultivated foods to replace animal-derived ingredients. A second activity involves establishing pluripotent stem cell lines and differentiation and …

more

Organisations and brands:

ProFuse Technology, an Israeli biotech company creating solutions for muscle growth in cultivated meat, announces it has been awarded a €2.4 million grant from the European Innovation Council (EIC) Transition program.

© ProFuse Technology
Cultivated, Cell-Cultured & Biotechnology

ProFuse Technology Awarded €2.4M European Innovation Council Grant for Muscle Growth Solutions in Cultivated Meat

ProFuse Technology, an Israeli biotech company creating solutions for muscle growth in cultivated meat, announces it has been awarded a €2.4 million grant from the European Innovation Council (EIC) Transition program. The EIC Transition program, part of Horizon Europe, helps startups advance and validate new technologies as they transition from the laboratory to real-world application environments. Selected among hundreds of applicants, this prestigious grant acknowledges ProFuse’s cutting-edge technology and its ability to transform cultivated meat production with increased yields, shorter cycles, and reduced costs. The EIC grant will enable ProFuse to enhance its muscle cultivation technologies,  including expanding production capabilities for large-scale cultivated meat production, obtaining necessary safety regulatory approvals, and strengthening collaborations with other cultivated meat companies.  Guy Nevo Michrowski, co-founder and CEO of ProFuse Technology, shares, …

more

Organisations and brands:

© Rawpixel.com – stock.adobe.com

Cultivated Meat

South Korea Designates Regulation-Free Zone for Cultivated Meat to Boost Production & Safety

The South Korean government has announced the designation of a special regulatory-free zone in Gyeongsangbuk-do province to accelerate the production and commercialization of cultivated meat in the country. The zone, officially named the Gyeongbuk Cell-Cultivated Foods Regulatory-Free Special Zone (RFSZ), aims to address the legal obstacles facing the development of cell culture food products, establish global standards for these novel foods, and develop a skilled workforce for the cultivated meat industry. The cultivated meat RSFZ will be operational for the next five years (until December 2028) with a budget of ₩19.9 billion ($14.4 million) as reported by local media. Demonstrating safety Ten companies, including SeaWith, TissenBioFarm, and DaNAgreen, will demonstrate the commercialization of cultivated meat, backed by R&D funding and tax breaks. Their goal will be to use cells from livestock …

more

Image courtesy of Mewery
Cultivated Meat

Mewery Announces Significant Progress in Cultivating Pork at Larger Scale

Czech cultivated meat company Mewery, known for its cultivated pork and microalgae burger, announces a key milestone in its product development: successfully establishing a stable cell line. The new cell line exhibits the most favorable response to Mewery’s proprietary co-cultivation technology, which involves pork cells and also microalgae cells used for a proprietary serum-free medium. Vladislav Strmiska, CSO at Mewery, comments: “This achievement represents another important step forward in our ongoing efforts to bring cultivated meat to consumers.“ Meat without animals As the company explains, a stable cell line is a population of cells that can continuously grow and retain their desired properties over many generations. This continuous growth eliminates the need to take cell samples from animals, making cultivated meat a more sustainable and ethical alternative …

more

Organisations and brands:

new zealand's biotech company opo bio's team in a photo shoot outdoors

© Opo Bio
Cultivated Meat

Opo Bio Introduces Porcine Cell Range Sourced From New Zealand “High-Health Status” Livestock

Opo Bio, New Zealand’s first company to develop non-GM cell lines for the cultivated meat industry, has launched Opo-Oink, a porcine cell range for cultivated pork production.  The initial selection of Opo-Oink includes primary cells from pigs, such as satellite cells, pre-adipocytes, and fibroblasts, sourced from local livestock with high-health status. “At Opo, we believe in ethical standards and traceability. That’s why all our animal donors are raised with utmost care and integrity on our partner farms throughout Aotearoa, New Zealand,” says Opo Bio. Commercially available cell lines Opo Bio was founded in July 2022 by Dr. Olivia Ogilvie (CEO), Dr. Laura Domigan (CSO), and Dr. Vaughan Feisst (CTO) to develop primary cells and cell lines, starting with bovine and porcine products. According to the …

more

Organisations and brands:

Myodenovo aims to grows cultivated meat using plant-based scaffolds

© Ilia-Nesolenyi-stock.adobe.com
Cultivated, Cell-Cultured & Biotechnology

ProFuse Technology Launches Pioneering Bovine Cell Line for Cultivated Beef

ProFuse Technology, an Israeli biotech specializing in muscle tissue growth, announces the launch of a new bovine cell line for cultivating beef. Branded as PROFUSE-B8 and claimed as a pioneering development, the cell line arises from spontaneously immortalized bovine myoblast cells without using genetic modification technology. As explained by the firm, the bovine cell line has undergone extensive research and testing over two years, resulting in a stable and robust foundation for developing scalable and repeatable muscle-growing processes. Moreover, when combined with the PROFUSE-S1, a muscle differentiation media supplement, the B8 cell line is said to accelerate muscle tissue production, increasing efficiency in shorter times.  Enhancing muscle growth  Established in 2021 by Tamar Eigler-Hirsh, CTO and co-founder, and Guy Nevo Michrowski, the company’s CEO; ProFuse …

more

Organisations and brands:

a graphic of a brown cow and a mark on its back that measures the wound inflicted to take a live cells sample

© Mosa Meat
Science

New Scientific Review by Mosa Meat Discusses Challenges in Cell Biology for Cultivated Meat

A new scientific review, Advances and Challenges in Cell Biology for Cultured Meat, by the Cell Biology team at Dutch biotech company Mosa Meat, highlights the importance of a detailed understanding and accurate manipulation of cell biology in designing cultivated meat bioprocesses.  Despite significant interest and breakthroughs in the field, the paper argues that numerous challenges remain at all stages of biomanufacturing, including the cell biology process.  To shed light on the advancements in this area, the review focuses explicitly on identifying suitable starting cell types, tuning proliferation and differentiation conditions, and optimizing cell-biomaterial interactions for creating nutritious and enticing cultivated meat products.  Additionally, the paper explores the emerging field of cultivated meat and its potential to revolutionize meat production if coordinated scientific efforts solve the …

more

Organisations and brands:

Steakholder cultivated steak on plate

image credit Shlomi Arbiv
Company News

Steakholder Foods Submits Patent for Immortal Bovine Cell Line, Says “It’s a Paradigm Shift” for Future Food

Israeli deep tech Steakholder Foods Ltd., known for its 3D printing technology, yesterday announced it had submitted a provisional patent for immortal bovine cell lines, with the purpose of providing a stable, renewable source for generating different tissues. Steakholder announced back in August 2022 that it was working on the development of cultivated pork products using a new line of porcine stem cells. It states that this current move represents a “significant step in making commercial-scale cultivated meat production a reality”, claiming it paves the way for scale, repeatability, and growth. The patent is said to present immortal cell lines that can generate a broad array of tissues including both muscle and fat, and to enhance the growth capacity of bovine cells resulting in immortalization …

more

Organisations and brands:

a graphic of a brown cow and a mark on its back that measures the wound inflicted to take a live cells sample

© Mosa Meat
Cultivated Meat

GFI Report Highlights Challenges of Sourcing Cell Lines for Cultivated Meat

The latest GFI cultivated meat report offers insights into cell line availability, desired qualities, sourcing issues, regulatory hurdles, and religious certifications — all challenges cultivated meat manufacturers face since there are very few commercial cell lines available. GFI experts conducted an industry-wide survey to address the lack of publicly available data on cell lines in the cultivated meat industry. They analyzed answers from 44 companies, providing “a first-of-its-kind portrait” of the progress, preferences, and hurdles of the industry as it seeks to scale up. “A deep dive into the companies’ responses also illuminates a regrettable reality: There is almost certainly significant duplication of effort with similar species, cell types, and product characteristics being pursued by many companies, and cell line development largely being conducted through resource-intensive …

more