Japanese Scientists Develop Low-Cost Medium to Grow Muscle Cells Without Animal Serum
Japanese scientists have developed a new co-culturing system using rat cells and cyanobacteria to create a low-cost alternative to animal serum for cell growth. Fetal bovine serum has contamination risks and waste accumulation, and is very costly. In addition, it does not align with the promise of producing meat without killing animals. Rat liver cells can also secrete the proteins (growth factors) needed for muscle cell growth, providing a serum alternative for cultivated meat production. However, they produce waste metabolites, like lactate and ammonia, which hinder muscle cell growth. “Although more growth factor-secreting cells and longer cultivation produce larger amounts of growth factors, the downside is that the cells also produce waste products like lactate and ammonia into the medium at the same time, which eventually …
