Researchers Develop Hollow Fiber Bioreactor to Improve Cultivated Meat Texture and Scale
Researchers at the University of Tokyo have developed a bioreactor that mimics a circulatory system, improving the production of cultivated meat by ensuring even nutrient and oxygen delivery to tissues. This new approach, published in Trends in Biotechnology, allows the creation of over 10 grams of chicken muscle tissue, addressing key challenges in scaling up cultivated meat production. Hollow fibers for nutrient delivery “We’re using semipermeable hollow fibers, which mimic blood vessels in their ability to deliver nutrients to the tissues,” explains senior author Shoji Takeuchi. These fibers, commonly used in medical applications such as dialysis, can now be adapted for biofabricating tissues. By precisely arranging the hollow fibers, the bioreactor ensures that nutrients and oxygen are uniformly distributed, preventing necrosis in thicker tissues, a …